Article

A shared genetic regulator of metabolism and addiction-related behavior in mice and humans

2025-12-24

Abstract excerpt

Substance use disorders and other mental health conditions often co-occur with metabolic disorders, suggesting shared biological underpinnings 1 . These heightened behavioral and physiological responses may have evolved to promote survival during resource scarcity but can become maladaptive in modern environments 2 . The genetic mechanisms linking these traits have remained elusive. Here, we show that a variable...

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Literature Corpus work: 22c2e3d3-70d0-5af6-bf35-d60ab626f015
DOI: 10.64898/2025.12.23.696269

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