Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice

1 May 2023

Abstract excerpt

Physical activity is associated with beneficial adaptations in human and rodent metabolism. We studied over 50 complex traits before and after exercise intervention in middle-aged men and a panel of 100 diverse strains of female mice. Candidate gene analyses in three brain regions, muscle, liver, heart, and adipose tissue of mice indicate genetic drivers of clinically relevant traits, including volitional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Genetics and Physical Performance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37178122
DOI: 10.1016/j.celrep.2023.112499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conserved multi-tissue transcriptomic adaptations to exercise training in humans and micePMID 37178122Read ↗

A conserved transcriptomic model defines metabolic resilience and vulnerability in obesitySemantic proximity Read ↗

Type 2 Diabetes and Obesity Alter Exercise Training-Induced Transcriptional Adaptations to Subcutaneous White Adipose TissueSemantic proximity Read ↗

Temporal dynamics of the multi-omic response to endurance exercise training across tissuesSemantic proximity Read ↗

Genetic background and sex control the outcome of high-fat diet feeding in miceSemantic proximity Read ↗

Transcriptome analysis of the adipose tissue in a mouse model of metabolic syndrome identifies gene signatures related to disease pathogenesisSemantic proximity Read ↗

Advances in Exercise, Fitness, and Performance Genomics in 2015Semantic proximity Read ↗

The 'Omics' of Voluntary Exercise: Systems Approaches to a Complex Phenotype.Semantic proximity Read ↗

The Effects of Sex and Diet on Physiology and Liver Gene Expression in Diversity Outbred MiceSemantic proximity Read ↗

The potential of integrating human and mouse discovery platforms to advance our understanding of cardiometabolic diseases.Semantic proximity Read ↗

Comparative multi-tissue profiling reveals extensive tissue-specificity in transcriptome reprogramming during thermal adaptationSemantic proximity Read ↗

A candidate syntenic genetic locus is associated with voluntary exercise levels in mice and humans.Semantic proximity Read ↗

Translational potential of mouse models of human metabolic diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.