Article

Genetics of cerebral small vessel disease

2018-01-01

Abstract excerpt

Cerebral small vessel disease (SVD) is a leading cause of stroke and vascular dementia. The majority of cases are sporadic, occurring in the elderly hypertensive population. However, there also exist patients with familial disease. The most common form is Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), caused by mutations in the NOTCH3 gene. In recent years, ot...

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Literature Corpus work: 8e0b52a8-ea94-5f49-9a7e-7ef4eab2f211
DOI: 10.17863/cam.30570

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