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Data-driven identification of predictive risk biomarkers for subgroups of osteoarthritis using an interpretable machine learning framework: a UK biobank study

2023-08-10

Abstract excerpt

<title>Abstract</title> <p>Osteoarthritis (OA) is increasing in prevalence and has a severe impact on patients’ lives. However, our understanding of biomarkers driving OA risk remains limited. We developed a model predicting the five-year risk of OA, integrating clinical, lifestyle and biomarker data from the UK Biobank (19,120 patients with OA, ROC-AUC:0.72 95%CI (0.71 – 0.73)). Higher age, BMI, and prescription...

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Literature Corpus work: 22acae3f-3d68-5c0c-a8ab-d857df30e2b3
DOI: 10.21203/rs.3.rs-3230959/v1

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