Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers.

doi:10.1136/bmjopen-2019-035101

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Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers.

BMJ open - 28 Jul 2020

van Helvoort Eefje M, van Spil Willem E, Jansen Mylène P, Welsing Paco M J, Kloppenburg Margreet, Loef Marieke, Blanco Francisco J, Haugen Ida K, Berenbaum Francis, Bacardit Jaume, Ladel Christoph H, Loughlin John, Bay-Jensen Anne C, Mobasheri Ali, Larkin Jonathan, Boere Janneke, Weinans Harrie H, Lalande Agnes, Marijnissen Anne C A, Lafeber Floris P J G

Abstract excerpt

PURPOSE: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (APPROACH) consortium intends to prospectively describe in detail, preselected patients with knee osteoarthritis (OA), using conventional and novel clinical, imaging, and biochemical markers, to support OA drug development. PARTICIPANTS: APPROACH is a prospective cohort study including 297 patients with tibiofemoral OA,...

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PMID: 32723735
DOI: 10.1136/bmjopen-2019-035101
PMCID: PMC7389775

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