Article

A systems immunology analysis of Alzheimer’s disease reveals an age- and environmental exposure-independent disturbance in B cell maturation

2025-06-17

Abstract excerpt

Alzheimer’s disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal models, and clinical investigation suggests a neuroimmunological component to disease, with links to the peripheral immune system. Here we applied a systems immunology approach to determine the immunological correlates of Alzheimer’s di...

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Literature Corpus work: 22a5904b-109a-5539-ae25-637986d6ba74
DOI: 10.1101/2025.06.16.25329692

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