Article

DiSCERN - Deep Single Cell Expression ReconstructioN for improved cell clustering and cell subtype and state detection

2022-03-09

Abstract excerpt

Single cell sequencing provides detailed insights into biological processes including cell differentiation and identity. While providing deep cell-specific information, the method suffers from technical constraints, most notably a limited number of expressed genes per cell, which leads to suboptimal clustering and cell type identification. Here we present DISCERN, a novel deep generative network that reconstructs...

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Literature Corpus work: 17314574-9856-5986-b2b7-a91a4609a2d3
DOI: 10.1101/2022.03.09.483600

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