Article

Stereochemical diversity as a source of discovery in chemical biology

2022-01-01

Abstract excerpt

Chirality is an inherent aspect of biology, and interactions between biomolecules are often influenced by stereochemistry and topographic complexity. This has implications for how small-molecule libraries are assembled for screening campaigns in chemical biology and drug discovery. Here we review the state of the field in the context of harnessing chirality as a source of chemical information at the chemistry-biol...

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Literature Corpus work: 22267c9e-4f74-50b9-a1a7-1e06db94c6de
DOI: 10.1016/j.crchbi.2022.100028

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