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Article

PIN1 Drives Cellular Plasticity and Immune Modulation in Chronic Pancreatitis

2025-05-14

Abstract excerpt

<h4>Background and Aims</h4> Chronic pancreatitis (CP) is characterized by inflammation, fibrosis, and acinar-to-ductal metaplasia (ADM). PIN1, known to drive oncogenic signaling and cellular plasticity in cancer, has an unexplored role in CP. This study investigates PIN1’s expression and function in CP pathogenesis using human tissues and mouse models. <h4>Methods</h4> PIN1 expression was assessed in human CP t...

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Identifiers and source

Literature Corpus work
21dc9a22-c7cb-5ba6-94ec-6719424e2666
DOI
10.1101/2025.05.13.653850
Open publication

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PIN1 Drives Cellular Plasticity and Immune Modulation in Chronic PancreatitisDOI 10.1101/2025.05.13.653850
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