Article
A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen capture
2024-06-07
Abstract excerpt
Nanoparticle presentation systems offer the potential to develop new vaccines rapidly in response to emerging diseases, a public health need that has become increasingly evident in the wake of the COVID-19 pandemic. Previously, we reported a nanoparticle scaffold system termed VelcroVax. This was constructed by insertion of a high affinity SUMO binding protein (Affimer), able to recognise a SUMO peptide tag, into...
Topics
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- Bacteriophages and microbial interactions
- Biochemical and Structural Characterization
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- Respiratory viral infections research
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
Identifiers and source
- Literature Corpus work
- 21b1b539-0bc6-5297-aba5-83aca05abf57
- DOI
- 10.1101/2024.06.07.597873
