Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toolbox for Non-Intrusive Structural and Functional Analysis of Recombinant VLP Based Vaccines: A Case Study with Hepatitis B Vaccine

6 Apr 2012

Abstract excerpt

BACKGROUND: Fundamental to vaccine development, manufacturing consistency, and product stability is an understanding of the vaccine structure-activity relationship. With the virus-like particle (VLP) approach for recombinant vaccines gaining popularity, there is growing demand for tools that define their key characteristics. We assessed a suite of non-intrusive VLP epitope structure and function characterization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Immunotherapy and Immune Responses
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22493667
DOI: 10.1371/journal.pone.0033235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toolbox for Non-Intrusive Structural and Functional Analysis of Recombinant VLP Based Vaccines: A Case Study with Hepatitis B VaccinePMID 22493667Read ↗

Virus-like particles: flexible platforms for vaccine developmentSemantic proximity Read ↗

Recent Progress on the Versatility of Virus-Like ParticlesSemantic proximity Read ↗

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriersSemantic proximity Read ↗

Tailored Viral-Like Particles as Drivers of Medical BreakthroughsSemantic proximity Read ↗

Innovations in structure-based antigen design and immune monitoring for next generation vaccines.Semantic proximity Read ↗

Virus‐like particles as powerful vaccination strategy against human virusesSemantic proximity Read ↗

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccinesSemantic proximity Read ↗

Virus-like particle-based human vaccines: quality assessment based on structural and functional propertiesSemantic proximity Read ↗

Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine designSemantic proximity Read ↗

A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen captureSemantic proximity Read ↗

Virus‑like particles as a vaccine delivery system: Myths and factsSemantic proximity Read ↗

Risk-free polio vaccine: Recombinant expression systems for production of stabilised virus-like particlesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.