Back to search

Article

Seasonal Human Coronaviruses OC43, 229E, and NL63 Induce Cell Surface Modulation of Entry Receptors and Display Host Cell-Specific Viral Replication Kinetics

2023-11-22

Abstract excerpt

<h4>ABSTRACT</h4> The emergence of the COVID-19 pandemic prompted increased interest in seasonal human coronaviruses. 229E, OC43, NL63 and HKU1 are endemic seasonal coronaviruses that cause the common cold and are associated with generally mild respiratory symptoms. In this study, we identified cell lines that exhibited cytopathic effects (CPE) upon infection by three of these coronaviruses and characterized thei...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
219fb090-18e3-5964-b220-9f16c6152000
DOI
10.1101/2023.11.20.567923
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Seasonal Human Coronaviruses OC43, 229E, and NL63 Induce Cell Surface Modulation of Entry Receptors and Display Host Cell-Specific Viral Replication KineticsDOI 10.1101/2023.11.20.567923
Seasonal human coronaviruses OC43, 229E, and NL63 induce cell surface modulation of entry receptors and display host cell-specific viral replication kineticsSemantic proximity
Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strainsSemantic proximity
Interferon signaling in the nasal epithelium distinguishes among lethal and common cold coronaviruses and mediates viral clearanceSemantic proximity
One for all – Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory virusesSemantic proximity
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entrySemantic proximity
Recapitulating infection, thermal sensitivity and antiviral treatment of seasonal coronaviruses in human airway organoidsSemantic proximity
Isolation and Characterization of Current Human Coronavirus Strains in Primary Human Epithelial Cell Cultures Reveal Differences in Target Cell TropismSemantic proximity
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing AntibodiesSemantic proximity
Human Coronavirus EMC Does Not Require the SARS-Coronavirus Receptor and Maintains Broad Replicative Capability in Mammalian Cell LinesSemantic proximity
Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS CoronavirusSemantic proximity
Human coronaviruses: Origin, host and receptorSemantic proximity
Entry of Human Coronavirus NL63 into the CellSemantic proximity
Select a neighboring publication to make it the new centre.