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Article

Entry of Human Coronavirus NL63 into the Cell

15 Nov 2017

Abstract excerpt

ABSTRACT The first steps of human coronavirus NL63 (HCoV-NL63) infection were previously described. The virus binds to target cells by use of heparan sulfate proteoglycans and interacts with the ACE2 protein. Subsequent events, including virus internalization and trafficking, remain to be elucidated. In this study, we mapped the process of HCoV-NL63 entry into the LLC-Mk2 cell line and ex vivo three-dimensional...

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PMID: 29142129
DOI: 10.1128/jvi.01933-17

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