Article

Iron Drives Anabolic Metabolism Through Active Histone Demethylation and mTORC1

2022-09-14

Abstract excerpt

<title>Abstract</title> <p>All living cells require a minimal iron threshold to sustain anabolic metabolism. However, the mechanisms by which cells sense iron to regulate anabolic processes are unclear. Here, we report a universal eukaryotic pathway for iron sensing in which molecular iron is required to sustain active histone demethylation and maintain the expression of critical components of the pro-anabolic mT...

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Literature Corpus work: 21959214-0ca0-5fcb-8a68-81fa6e341b54
DOI: 10.21203/rs.3.rs-2042947/v1

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