Article
ALDH2/ADH2 Polymorphism Associated with Vasculopathy and Neuropathy in Type 2 Diabetes
2004-08-01
Abstract excerpt
In the history of diabetes, chlorpropamide alcohol flushing test (CPAF) was a big topic in the 1970s to 1980s. Alcohol tolerance after chlorpropamide has prognostic significance, with the intolerant group (CPAF‐positive group) being less prone to develop vascular complication than the tolerant group (CPAF‐negative group). A mechanism of CPAF has been regarded as the inhibition of aldehyde dehydrogenase 2 (ALDH2) b...
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Identifiers and source
- Literature Corpus work
- 21756a31-dbea-5f78-a05d-19759f10a732
- DOI
- 10.1111/j.1530-0277.2004.tb03227.x
