Article
Meta-Analysis on the Association of ALDH2 Polymorphisms and Type 2 Diabetic Mellitus, Diabetic Retinopathy.
International journal of environmental research and public health - 8 Feb 2017
Li Guang-Yi, Li Zi-Bo, Li Fang, Dong Li-Ping, Tang Liang, Xiang Ju, Li Jian-Ming, Bao Mei-Hua
Abstract excerpt
Type 2 diabetic mellitus (T2DM) is a disease with high prevalence and a major cause for death worldwide. Diabetic retinopathy (DR) is one of the major manifestation of diabetes. Aldehyde dehydrogenease 2 (ALDH2) detoxifies aldehyde produced during ethanol metabolism and oxidative stress. It has been found that the polymorphism in ALDH2 rs671 is probably associated with the risk of T2DM and DR. However, a lot of...
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