Article
3D bioprinted CRC model brings to light the replication necessity of an oncolytic vaccinia virus encoding FCU1 gene to exert an efficient anti-tumoral activity
2023-12-06
Abstract excerpt
The oncolytic virus represents a promising therapeutic strategy involving the targeted replication of viruses to eliminate cancer cells, while preserving healthy ones. Despite ongoing clinical trials, this approach encounters significant challenges. This study delves into the interaction between an oncolytic virus and the extracellular matrix (ECM). A three-dimensional colorectal cancer model, enriched with ECM th...
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Identifiers and source
- Literature Corpus work
- 216cda02-af67-50dc-88de-b21036571406
- DOI
- 10.21203/rs.3.rs-3685530/v1
