Article

Pink1/Parkin deficiency alters circulating lymphocyte populations and increases platelet-T cell aggregates in rats

2024-05-30

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD) is the most common progressive neurodegenerative movement disorder and results from the selective loss of dopaminergic neurons in the substantia nigra pars compacta. Pink1 and Parkin are proteins that function together in mitochondrial quality control, and when they carry loss-of-function mutations lead to familial forms of PD. While much research has focused on...

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Literature Corpus work: 210eb722-a804-5645-a3f3-4233c3d265b7
DOI: 10.21203/rs.3.rs-4431604/v1

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