Article

Identification of a natural antagonist for signal transducer and activator of transcription 3 (STAT3) by computational approach

2023-01-01

Abstract excerpt

The transcription factor family includes the cluster protein signal transducer and activator of transcription 3 (STAT3). Colorectal cancer (CRC) is predisposed to develop and spread when STAT 3 is abnormally activated because it speeds up cell division, prevents differentiation, and suppresses apoptosis. Only a small number of phytochemicals such as curcumin have been solidly demonstrated in clinical trials to low...

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Literature Corpus work: 20e9bcee-f994-5d00-a751-4a90089fe6f2
DOI: 10.1016/j.rechem.2023.100970

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