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High-throughput Single-Virion DNA-PAINT Reveals Structural Diversity, Cooperativity and Flexibility during Selective Packaging in Influenza

2025-02-11

Abstract excerpt

<h4>ABSTRACT</h4> Influenza A, a negative-sense RNA virus, has a genome that consists of eight single-stranded RNA segments. Influenza co-infections can result in re-assortant viruses that contain gene segments from multiple strains, causing pandemic outbreaks with severe consequences for human health. The outcome of re-assortment is likely influenced by a selective sequence-specific genome packaging mechanism. T...

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Literature Corpus work
20d8103c-4268-5602-8744-1b7bb31a1268
DOI
10.1101/2025.02.11.637713
Open publication

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High-throughput Single-Virion DNA-PAINT Reveals Structural Diversity, Cooperativity and Flexibility during Selective Packaging in InfluenzaDOI 10.1101/2025.02.11.637713
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