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Article

Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis.

Molecular and cellular biology - 1 Jan 2015

Lawan Ahmed, Zhang Lei, Gatzke Florian, Min Kisuk, Jurczak Michael J, Al-Mutairi Mashael, Richter Patric, Camporez Joao Paulo G, Couvillon Anthony, Pesta Dominik, Roth Flach Rachel J, Shulman Gerald I, Bennett Anton M

Abstract excerpt

The liver plays a critical role in glucose metabolism and communicates with peripheral tissues to maintain energy homeostasis. Obesity and insulin resistance are highly associated with nonalcoholic fatty liver disease (NAFLD). However, the precise molecular details of NAFLD remain incomplete. The p38 mitogen-activated protein kinase (MAPK) and c-Jun NH2-terminal kinase (JNK) regulate liver metabolism. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25312648
DOI: 10.1128/MCB.00503-14
PMCID: PMC4295383

Genes

FGF21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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