Article

ZMYND10 functions in a chaperone relay during axonemal dynein assembly

2017-12-13

Abstract excerpt

Molecular chaperones promote the folding and macromolecular assembly of a diverse set of substrate ‘client’ proteins. How the ubiquitous chaperone machinery directs its activities towards a specific set of substrates and whether this selectivity could be targeted for therapeutic intervention is of intense research. Through the use of mouse genetics, imaging and quantitative proteomics we uncover that ZMYND10 is a...

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Literature Corpus work: 20ac6009-2ea0-5f16-8623-354175be3305
DOI: 10.1101/233718

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