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Expression Profiling of IDH, p53, ATRX, and KI-67 Immunostains as Potential Grid for Molecular Subtyping of Adult Diffuse Gliomas from Pakistan

2023-04-07

Abstract excerpt

<h4>Background: </h4> The classification of gliomas is changing profoundly and has been shifted from histological criteria only; to morphological and molecular markers. The routine everyday approach nowadays for diagnosing diffuse gliomas begins with immunohistochemistry (IHC) for IDH1, ATRX, and p53, as these substitute molecular testing for classification. Moreover, the Ki-67 immunomarker is a useful accessory m...

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Literature Corpus work
20ac2053-2380-58cb-9a5c-2967f91b9d08
DOI
10.21203/rs.3.rs-2717800/v1
Open publication

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