Article
Practice of IDH1, ATRX, and P53 Immunohistochemistry in Integrated Diagnosis of Adult Diffuse Gliomas: Single Center Study.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2023
Shabanzadeh Nejabad Zohreh, Mabroukzadeh Kavari Hoda, Saffar Hana, Tavangar Seyed Mohammad, Sefidbakht Salma, Khoshnevisan Alireza, Zare-Mirzaie Ali, Vasei Mohammad, Jafari Ensieh, Yaghmaii Marjan, Saffar Hiva
Abstract excerpt
Diffuse gliomas exhibit different molecular and genetic profiles with a wide range of heterogeneity and prognosis. Recently, molecular parameters including ATRX, P53, and IDH mutation status or absence or presence of 1p/19q co-deletion have become a crucial part of the diagnosis of diffuse glioma. In the present study, we tried to analyze the routine practice of the above-mentioned molecular markers focusing on...
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