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Article

Grading of adult diffuse gliomas according to the 2021 WHO Classification of Tumors of the Central Nervous System.

Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2022

Komori Takashi

Abstract excerpt

The grading of gliomas based on histological features has been a subject of debate for several decades. A consensus has not yet been reached because of technical limitations and inter-observer variations. While the traditional grading system has failed to stratify the risk of IDH-mutant astrocytoma, canonical histological and proliferative markers may be applicable to the risk stratification of IDH-wild-type...

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Identifiers

PMID: 34504304
DOI: 10.1038/s41374-021-00667-6

Genes

CDKN2A
EGFR
TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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