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Decoding Alzheimer’s Molecular Signatures through Bioinformatics and AI/ML-Assisted Structure-Based Discovery of SIRT2 Inhibitors for Alzheimer’s Disease

2026-03-06

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<title>Abstract</title> <p>Alzheimer’s disease (AD) is one of the neurodegenerative disorder with complicated pathogenesis. The present study aimed to explore key pathways and genes in AD pathogenesis, which could be potential targets for novel AD treatments. Differentially expressed genes (DEGs) of RNA-sequencing dataset (GSE276756) obtained from Gene Expression Omnibus (GEO) were identified using the DESeq2 R b...

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Literature Corpus work
4a9c2de0-9e7f-5f77-95ea-3ded72785b68
DOI
10.21203/rs.3.rs-9039869/v1
Open publication

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Decoding Alzheimer’s Molecular Signatures through Bioinformatics and AI/ML-Assisted Structure-Based Discovery of SIRT2 Inhibitors for Alzheimer’s DiseaseDOI 10.21203/rs.3.rs-9039869/v1
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