Diffusion-based structural connectivity patterns of multiple sclerosis phenotypes.

doi:10.1136/jnnp-2023-331531

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Article

Diffusion-based structural connectivity patterns of multiple sclerosis phenotypes.

Journal of neurology, neurosurgery, and psychiatry - 1 Nov 2023

Martinez-Heras Eloy, Solana Elisabeth, Vivó Francesc, Lopez-Soley Elisabet, Calvi Alberto, Alba-Arbalat Salut, Schoonheim Menno M, Strijbis Eva M, Vrenken Hugo, Barkhof Frederik, Rocca Maria A, Filippi Massimo, Pagani Elisabetta, Groppa Sergiu, Fleischer Vinzenz, Dineen Robert A, Bellenberg Barbara, Lukas Carsten, Pareto Deborah, Rovira Alex, Sastre-Garriga Jaume, Collorone Sara, Prados Ferran, Toosy Ahmed, Ciccarelli Olga, Saiz Albert, Blanco Yolanda, Llufriu Sara

Abstract excerpt

BACKGROUND: We aimed to describe the severity of the changes in brain diffusion-based connectivity as multiple sclerosis (MS) progresses and the microstructural characteristics of these networks that are associated with distinct MS phenotypes. METHODS: Clinical information and brain MRIs were collected from 221 healthy individuals and 823 people with MS at 8 MAGNIMS centres. The patients were divided into four...

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PMID: 37321841
DOI: 10.1136/jnnp-2023-331531

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