Article

A hypercubic Mk model framework for capturing reversibility in disease, cancer, and evolutionary accumulation modelling

2024-07-02

Abstract excerpt

Accumulation models, where a system progressively acquires binary features over time, are common in the study of cancer progression, evolutionary biology, and other fields. Many approaches have been developed to infer the accumulation pathways by which features (for example, mutations) are acquired over time. However, most of these approaches do not support reversibility: the loss of a feature once it has been acq...

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Literature Corpus work: 205494bb-fa90-51f5-96ed-c63bb53125cb
DOI: 10.1101/2024.06.27.600959

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