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Article

Inferring high-dimensional pathways of trait acquisition in evolution and disease

2018-09-05

Abstract excerpt

The explosion of data throughout the sciences provides unprecedented opportunities to learn about the dynamics of evolution and disease progression. Here, we describe a highly generalisable statistical platform to infer the dynamic pathways by which many, potentially interacting, discrete traits are acquired or lost over time in biological processes. The platform uses HyperTraPS (hypercubic transition path samplin...

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Identifiers and source

Literature Corpus work
33921fc6-a597-5c11-9925-6f3ce7b2027a
DOI
10.1101/409656
Open publication

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Inferring high-dimensional pathways of trait acquisition in evolution and diseaseDOI 10.1101/409656
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