Article
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy.
Biological chemistry - 25 Jun 2024
Wali Ruheen, Xu Hang, Cheruiyot Cleophas, Saleem Hafiza Nosheen, Janshoff Andreas, Habeck Michael, Ebert Antje
Abstract excerpt
Integration of multiple data sources presents a challenge for accurate prediction of molecular patho-phenotypic features in automated analysis of data from human model systems. Here, we applied a machine learning-based data integration to distinguish patho-phenotypic features at the subcellular level for dilated cardiomyopathy (DCM). We employed a human induced pluripotent stem cell-derived cardiomyocyte...
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