Article

Sustained Generation of Neurons Destined for Neocortex with Oxidative Metabolic Upregulation upon Filamin Abrogation

2023-08-12

Abstract excerpt

<h4>Summary</h4> Neurons in the neocortex are generated during embryonic development. While the adult ventricular-subventricular zone (V-SVZ) contains cells with neural stem/progenitors’ characteristics, it remains unclear whether it has the capacity of producing neocortical neurons. Here we show that the generation of neurons exhibiting transcriptomic resemblance to neurons of the upper cortical layers continues...

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Literature Corpus work: 1ff0eca9-c97c-5f75-97b3-6c8731344dd9
DOI: 10.1101/2023.08.09.552667

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