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The LncRNA RMST-miR-4295-ITPR1 axis: a key mechanism in regulating autophagy in triple-negative breast cancer cells

26 Apr 2025

Abstract excerpt

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with poor prognosis and limited treatment options. Autophagy targeting plays a complex role in tumor resistance. The role of long noncoding RNA (LncRNA) RMST in TNBC progression and its potential involvement in autophagy regulation remain largely unexplored. METHODS: We performed a bioinformatics analysis using...

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PMID: 40287640
DOI: 10.1186/s12885-025-14189-7

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