Article

Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway

2020-04-23

Abstract excerpt

<title>Abstract</title> <p>Background: Triple-negative breast cancer(TNBC) is a great threat to global women’s health due to its high metastatic potential. Epithelial-to-mesenchymal transition (EMT) is considered as a key event in the process of metastasis. So the pharmacological targeting of EMT might be a promising strategy in improving the therapeutic efficacy of TNBC. Here, we investigated the effect of shiko...

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Literature Corpus work: 64d240c9-9dfe-570e-9227-26372836e1d0
DOI: 10.21203/rs.3.rs-23832/v1

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