Article

A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discovery

2019-12-11

Abstract excerpt

Approximately 10% of the world’s population is at risk of schistosomiasis, a disease of poverty caused by the Schistosoma parasite. To facilitate drug discovery for this complex flatworm, we developed an automated high-content screen to quantify the multidimensional responses of Schistosoma mansoni post-infective larvae (somules) to chemical insult. We describe an integrated platform to process worms at scale, c...

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Literature Corpus work: 1fe438fb-48de-5f93-8be0-fca808091fee
DOI: 10.1101/872069

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