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Article

Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery.

Parasites & vectors - 22 Oct 2019

Maccesi Martina, Aguiar Pedro H N, Pasche Valérian, Padilla Melody, Suzuki Brian M, Montefusco Sandro, Abagyan Ruben, Keiser Jennifer, Mourão Marina M, Caffrey Conor R

Abstract excerpt

BACKGROUND: Over the past five years, as a public service to encourage and accelerate drug discovery for diseases of poverty, the Medicines for Malaria Venture (MMV) has released box sets of 400 compounds named the Malaria, Pathogen and Stasis Boxes. Here, we screened the Pathogen Box against the post-infective larvae (schistosomula) of Schistosoma mansoni using assays particular to the three contributing...

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Identifiers

PMID: 31640761
DOI: 10.1186/s13071-019-3747-6
PMCID: PMC6805474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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