Article
Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis.
BMC genomics - 1 Jan 2012
Lee Hyokyeong, Moody-Davis Asher, Saha Utsab, Suzuki Brian M, Asarnow Daniel, Chen Steven, Arkin Michelle, Caffrey Conor R, Singh Rahul
Abstract excerpt
BACKGROUND: Neglected tropical diseases, especially those caused by helminths, constitute some of the most common infections of the world's poorest people. Development of techniques for automated, high-throughput drug screening against these diseases, especially in whole-organism settings, constitutes one of the great challenges of modern drug discovery. METHOD: We present a method for enabling high-throughput...
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