Article

CSF 14-3-3ζ is associated with tau pathology and elevated across the Alzheimer’s disease continuum

2022-12-21

Abstract excerpt

<title>Abstract</title> <p>Background 14-3-3 is a family of conserved proteins that consist of seven isoforms which are highly expressed in the brain, and 14-3-3ζ is one of the isoforms encoded by the YWHAZ gene. Previous studies demonstrated that 14-3-3ζ is deposited in the neurofibrillary tangles of Alzheimer’s disease (AD) brains, and that 14-3-3ζ interacts with tau from the purified neurofibrillary tangles o...

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Literature Corpus work: 1fb2de8a-d9c7-53c2-9bfb-843fbc5361fe
DOI: 10.21203/rs.3.rs-2229567/v2

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