Article
Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Feb 2020
Antonell Anna, Tort-Merino Adrià, Ríos José, Balasa Mircea, Borrego-Écija Sergi, Auge Josep M, Muñoz-García Cristina, Bosch Beatriz, Falgàs Neus, Rami Lorena, Ramos-Campoy Oscar, Blennow Kaj, Zetterberg Henrik, Molinuevo José L, Lladó Albert, Sánchez-Valle Raquel
Abstract excerpt
INTRODUCTION: Synaptic damage, axonal neurodegeneration, and neuroinflammation are common features in Alzheimer's disease (AD), frontotemporal dementia (FTD), and Creutzfeldt-Jakob disease (CJD). METHODS: Unicentric cohort of 353 participants included healthy control (HC) subjects, AD continuum stages, genetic AD and FTD, and FTD and CJD. We measured cerebrospinal fluid neurofilament light (NF-L), neurogranin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.