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The FTO-regulated circNFATC3/miR-23b-3p axis promotes RAI14-mediated gastric cancer progression via lipid metabolic reprogramming

2026-04-02

Abstract excerpt

<title>Abstract</title> <p> <bold>Aim</bold> To determine the mechanism by which fat mass and the obesity-associated protein (FTO)-regulated circNFATC3/miR-23b-3p axis influence RAI14-mediated gastric cancer (GC) progression. <bold>Methods</bold> Retinoic acid-induced protein 14 (RAI14), adenosine 5′-monophosphate-activated protein kinase (AMPK), mTOR (mTOR), sterol regulatory element-binding protein 1 (SREBP...

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Literature Corpus work
1f99898e-c669-5c14-9547-2af7bce4716d
DOI
10.21203/rs.3.rs-9252847/v1
Open publication

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