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Donor-derived CD19-CAR-T therapy in combination with TKI cure uncommon CRLF2r- Mixed Phenotype Acute Leukemia lineage switch to Ph+ Acute Lymphoblastic Leukemia

2026-03-11

Abstract excerpt

<title>Abstract</title> <p> Mixed phenotype acute leukemia (MPAL) is a rare hematologic malignancy characterized by the presence of a single population of cells expressing antigens of two or more lineages or by two or more populations of blast cells with different lineage features. Lineage transformation was seen in the patients diagnosed as MPAL with <italic>BCR::ABL1</italic> (Philadelphia chromosome) or <i...

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Literature Corpus work: 1f687926-3a75-5e1f-a2b3-88cc092cce69
DOI: 10.21203/rs.3.rs-8741783/v1

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