Article
Favorable response of a patient with primary B/myeloid mixed phenotype acute Leukemia to CD19-CAR-T: Case report and literature review.
Medicine - 15 Dec 2023
Wang Lixin, Pang Yanbin, Fang Chuling, Zhao Weiqiang, Xu Yuanyuan, Guo Xiao, Qiao Jingqiao, Mei Junhui, Wang Hongxin, Yu Chuan, Li Yisheng, Tang Zhixiong, Yu Li
Abstract excerpt
RATIONALE: Mixed phenotype acute leukemia (MPAL) is a rare and heterogeneous type of leukemia known for its poor prognosis. The optimal treatment strategy for this condition currently lacks consensus, leaving uncertainty in its management. Nonetheless, a potential therapeutic option for patients with refractory MPAL who express target antigens is donor-derived chimeric antigen receptor T (CAR-T) cell therapy....
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