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ADSC secretome constrains NK cell activity by attenuating IL-2–mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4

2023-05-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Mesenchymal stem cells (MSCs) have immunomodulatory properties and therapeutic effects on autoimmune diseases through their secreted factors, referred to as the secretome. However, the specific key factors of the MSC secretome and their mechanisms of action in immune cells have not been fully determined. Most <italic>in vitro</italic> experiments are being perfo...

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Literature Corpus work
1f5ac348-3b63-52b6-b225-c6c94ddd262f
DOI
10.21203/rs.3.rs-2843816/v1
Open publication

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ADSC secretome constrains NK cell activity by attenuating IL-2–mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4DOI 10.21203/rs.3.rs-2843816/v1
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