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Article

Influence of metabolically compromised Adipose derived stem cell secretome on islet differentiation and functionality.

Experimental cell research - 15 Jan 2022

Bhardwaj Gurprit, Vakani Mitul, Srivastava Abhay, Rawal Komal, Kalathil Amrita, Gupta Sarita

Abstract excerpt

Islet integrity plays a major role in maintaining glucose homeostasis and thus replenishment of damaged islets by differentiation of resident endocrine progenitors into neo islets regulates the islet functionality. Islet differentiation is affected by many factors including crosstalk with various organs by secretome. Adipose derived stem cells (ADSC) secrete a large array of factors in the extracellular milieu...

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Identifiers

PMID: 34896076
DOI: 10.1016/j.yexcr.2021.112970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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