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Article

Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages

12 May 2017

Abstract excerpt

BACKGROUND: Tuberculosis (TB) remains a significant global health concern and its diagnosis is challenging due to the limitations in the specificity and sensitivity of the current diagnostic tests. Exosomes are bioactive 30-100 nm vesicles produced by most cell types and are found in almost all human body fluids. Exosomal microRNAs (miRNAs) can transfer biological information between cells and tissues and may act...

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PMID: 28499455
DOI: 10.1186/s12967-017-1205-9

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