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Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access

1 Jun 2016

Abstract excerpt

Mycobacterium tuberculosis, the infectious agent of human tuberculosis is a master player in circumventing the defense mechanisms of the host immune system. The host-pathogen interaction in the case of an infection with M. tuberculosis is highly complex, involving dedicated mycobacterial virulence factors as well as the action of the innate and adapted immune systems, which determine the outcome of infection....

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PMID: 27247079
DOI: 10.1111/cmi.12622

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