Article

Targeting TFF3 in obstructive airway diseases: a computational approach to novel therapeutics

2024-01-31

Abstract excerpt

<h4>Background: </h4> Airway remodeling, a hallmark of chronic obstructive pulmonary disease (COPD) and Mustard lung disease, is influenced by the Trefoil Factor 3 (TFF3). This study sought to pinpoint a compound with minimal toxicity that can effectively suppress TFF3 expression and activity. Methods and Results We employed an integrative approach, combining gene expression analysis, molecular docking, and molec...

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Literature Corpus work: 1ed8b304-fc93-54e6-a63d-7bdf485c4d0f
DOI: 10.21203/rs.3.rs-3907985/v1

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