Article

An Integrative Multimodal Model for Early Diagnosis of Dementia and Differential Diagnosis of Alzheimer’s Disease Using Neuroimaging, Polygenic Risk, and Cognitive Assessments

2026-08-03

Abstract excerpt

<h4>Background</h4> Early diagnosis and etiological classification of dementia remain challenging, as clinicians typically lack tools to integrate cognitive, neuroimaging, and genetic data quantitatively. We developed and validated multimodal risk models to support early diagnosis of dementia and differential diagnosis of Alzheimer’s disease (AD) versus non-AD dementias in real-world clinical settings and transla...

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Literature Corpus work: 1ed04707-38aa-5acf-a98c-6a79053ab6fc
DOI: 10.64898/2026.07.31.26359317

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