Article

Integrative omics data analysis uncovers biomarker genes and potential candidate drugs for G3 medulloblastoma

2020-06-20

Abstract excerpt

Medulloblastoma (MB) is the most common malignant brain tumor in infants and children. Four molecular subtypes of MB are recognized: WNT, SHH, Group 3 (G3), and Group 4 (G4). Compared with WNT and SHH subtypes, G3 MBs exhibit significantly worse outcomes and higher metastatic rates, and there is no effective treatment yet. Moreover, G3 and G4 MBs are much more common in boys than girls, i.e., sex bias, which also...

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Identifiers and source

Literature Corpus work: 09355052-757a-5c09-a43a-e91d0cc824fd
DOI: 10.1101/2020.06.19.122515

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