Article

EVI-1-Mediated Up-Regulation of lncRNA TUG1 Interacts with miR-186-5p to Promote Proliferation and Drug Resistance in Pediatric Acute Myeloid Leukemia

2021-08-03

Abstract excerpt

<h4>Background: </h4> Deregulated lncRNAs have been well-documented to be closely associated with resistance to chemotherapeutic agents in malignancies including acute myeloid leukemia (AML). Herein, we intended to explore the roles and underlying mechanism of lncRNA taurine-upregulated gene 1 (TUG1) in pediatric AML cell adriamycin (ADR) resistance. <h4>Methods: </h4>: TUG1 and ecotropic viral integration site-1...

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Literature Corpus work: 1e97b1ef-9acf-5b91-aa40-2279f3bb0724
DOI: 10.21203/rs.3.rs-762990/v1

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