Article

A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral Neuropathy

2019-11-27

Abstract excerpt

Vincristine is a core chemotherapeutic drug administered to pediatric acute lymphoblastic leukemia patients. Despite its efficacy in treating leukemia, it can lead to severe peripheral neuropathy in a sub-group of the patients. Peripheral neuropathy is a debilitating and painful side-effect that can severely impact an individual’s quality of life. Currently, there are no established predictors of peripheral neurop...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1e7d4066-db85-50da-b31e-f0b7b562b6de
DOI: 10.1101/19013078

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral NeuropathyDOI 10.1101/19013078Read

Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk FactorSemantic proximity Read

Pharmacogenomics of Vincristine‐Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy GenesSemantic proximity Read

Predictive biomarkers of chemotherapy-induced peripheral neuropathy: a review.Semantic proximity Read

A machine learning model using SNPs obtained from a genome-wide association study predicts the onset of vincristine-induced peripheral neuropathy.Semantic proximity Read

Genetic Variants Associated With Vincristine‐Induced Peripheral Neuropathy in Two Populations of Children With Acute Lymphoblastic LeukemiaSemantic proximity Read

Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Studies Related to Vincristine-Induced Peripheral Neuropathy in Chinese Pediatric ALL Patients.Semantic proximity Read

Genetic factors influencing the development of vincristine-induced neurotoxicity.Semantic proximity Read

Chemotherapy-induced peripheral neurotoxicity in the era of pharmacogenomics.Semantic proximity Read

Pharmacogenomics of chemotherapy induced peripheral neuropathy using an electronic health record-derived definition: a genome-wide association study.Semantic proximity Read

The Pharmacogenomics of Vincristine-Induced Neuropathy: On Pins and Needles.Semantic proximity Read

Chemotherapy induced peripheral neuropathy : clinical aspects and molecular geneticsSemantic proximity Read

Genomic variations associated with risk and protection against vincristine-induced peripheral neuropathy in pediatric cancer patientsSemantic proximity Read